NATIONAL
CALIFORNIA
VENTURA
category
mechanism
- Blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle causing bronchodilation
indications
- Asthma and Chronic Obstructive Pulmonary Disease: Treatment of bronchospasm
contraindications
- Allergies: Soy/peanut allergy is NOT a contraindication with current preparations
dosing
Adult
Nebulized: 0.5 mg
Inhaler: 4-8 inhalations (68-136 mcg)
Pediatric:
Nebulized: 0.25 mg
Inhaler: 4 inhalations (68 mcg)
administration
Nebulizer: adjust nebulizer flow to deliver dosage over 5 to 15 minutes; use a mask device if patient unable to hold mouthpiece in mouth for administration. Compatible with albuterol in nebulizer.
Inhalers: Prime prior to first use, and whenever inhaler has not been used for >3 days by releasing 2 test sprays into the air. Does not require shaking.
Inhalers: Prime prior to first use, and whenever inhaler has not been used for >3 days by releasing 2 test sprays into the air. Does not require shaking.
onset
15 minutes
peak
1 to 2 hours
duration
Inhaler: 2 to 4 hours
Nebulization solution: 4 to 5 hours
notes
- Administration with albuterol: Can be administered with albuterol in nebulizer
- Allergy:There is no increased risk of allergic reaction with soy/peanut allergy. Older prepartions contained soy lecithin but current formulations do not.
dosage form
Nebulization Solution: 0.02% (2.5 mL)
Inhalation: 17 mcg/actuation
Inhalation: 17 mcg/actuation
brand name
Atrovent
adverse reactions
- Cardiovascular
- Angina
- Arrhythmias
- Hypertension
- Palpitations
- Gastrointestinal
- Nausea/Vomiting
- Central Nervous System
- Nervousness
- Restlessness
- Tremors
- Headache
- Insomnia
structure