NATIONAL
CALIFORNIA
VENTURA
category
mechanism
- Inhibits reabsorption of sodium and chloride in the kidneys which causes diuresis
indications
- Edema or volume overload due to heart failure, cirrhosis, or kidney disease
contraindications
- Anuria (patient produces no urine)
dosing
Oral, IV: 20 to 40 mg
administration
Oral or IV push
onset
IV: 5 minutes
Oral: 30 to 60 minutes
peak
IV: 30 minutes
Oral: 1 to 2 hours
duration
IV: 2 hour
Oral: 6 to 8 hours
notes
- Acute kidney injury: Loop diuretics, including furosemide, may lead to acute kidney injury due to fluid loss
- Fluid/electrolyte loss: May lead to profound diuresis, resulting in hypovolemia and electrolyte loss. Electrolyte disturbances (eg, hypocalcemia, hypokalemia, hypomagnesemia) may predispose a patient to serious cardiac arrhythmias.
dosage form
Solution, Injection: Generic: 10 mg/mL (2 mL, 4 mL, 10 mL)
Tablet, Oral: 20 mg, 40 mg, 80 mg
Tablet, Oral: 20 mg, 40 mg, 80 mg
brand name
Lasix
adverse reactions
- Hypersensitivity reactions
- There is a theoretical cross-reactivity between sulfa antibiotic and furosemide, however this may not actually occur, or the risk is extremely low
structure
