NATIONAL
CALIFORNIA
VENTURA
category
mechanism
- Binds with receptors at many sites within the CNS, increases pain threshold, alters pain reception, inhibits pain pathways
indications
- Pain management
contraindications
- Concurrent use or use within 14 days of a monoamine oxidase inhibitor (MAOI)
dosing
IV, IM, IO: 1 mcg/kg, maximum 100 mcg, repeat every 10 minutes for persistent pain to a max total dose of 200 mcg
administration
Administer slowly over 1 to 2 minutes; rapid IV infusion may result in skeletal muscle and chest wall rigidity, impaired ventilation, or respiratory distress/arrest.
onset
Immediate
peak
1 minute
duration
IM: 1 to 2 hours
IV: 0.5 to 1 hour
notes
- Reversal: Opiate antagonist drugs (naloxone) oxygen and resuscitation equipment should be readily available during the administration of fentanyl
- CNS depression: additive CNS depression may occur if used with other CNS depressants
dosage form
Injection Solution: 50 mcg/mL
adverse reactions
- Respiratory
- Apnea
- Hypoventilation
- Laryngospasm
- Cardiovascular
- Arrhythmia
- Hypertension
- Hypotension
- Nervous system
- Confusion
- Dizziness
- Drowsiness
- Gastrointestinal
- Abdominal pain
- Anorexia
- Constipation
- Diarrhea
- Nausea
- Vomiting
structure
