NATIONAL
CALIFORNIA
VENTURA
category
mechanism
- Increases cardiac output due to increased inotropy, chronotropy and dromotropy (beta-1 receptors)
- Relaxes smooth muscles of the respiratory tract (beta-2 receptors)
- Constricts vascular smooth muscle (alpha receptors)
- Increases coronary perfusion pressure during CPR by increasing aortic diastolic pressure
indications
- Anaphylaxis
- Symptomatic bradycardia or atrioventricular block
- Cardiac arrest
- Severe asthma
contraindications
- No absolute contraindications
dosing
Adult
Cardiac Arrest
IV, IO: 1 mg every 3 to 5 minutes until return of spontaneous circulation
Anaphylaxis
Bradycardia or atrioventricular block
Severe asthma
IV, IO: 10 mcg every 2 minutes
Pediatric
Cardiac Arrest
IV, IO: 0.01 mg/kg, maximum dose: 1 mg/dose; repeat every 3 to 5 minutes until return of spontaneous circulation
Anaphylaxis
Bradycardia or atrioventricular block
Severe asthma
IV, IO: 1 mcg/kg, maximum dose: 10 mcg/dose; every 2 minutes
administration
IV, IO
onset
rapid
duration
<5 minutes
notes
- Cardiovascular disease: Increases cardiac workload and myocardial oxygen demand - use with extreme caution in patients with myocardial ischemia, cardiomyopathy or cardiogenic shock.
- Older adults: Use with caution in older adults.
dosage form
1 mg/10 mL (10 mL) (1:10,000)
adverse reactions
- Cardiovascular
- Angina
- Arrhythmias (V-fib, V-tach)
- Hypertension
- Palpitations
- Tachycardia
- Gastrointestinal
- Nausea/Vomiting
- CNS
- Nervousness
- Restlessness
- Tremors
- Headache
structure
